| Reaction Details |
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 | Report a problem with these data |
| Target | Histidine-rich protein PFHRP-II |
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| Ligand | BDBM50003681 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_500704 (CHEMBL966920) |
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| IC50 | 26000±n/a nM |
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| Citation |  Sunduru, N; Srivastava, K; Rajakumar, S; Puri, SK; Saxena, JK; Chauhan, PM Synthesis of novel thiourea, thiazolidinedione and thioparabanic acid derivatives of 4-aminoquinoline as potent antimalarials. Bioorg Med Chem Lett19:2570-3 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histidine-rich protein PFHRP-II |
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| Name: | Histidine-rich protein PFHRP-II |
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| Synonyms: | HRP1_PLAFA | Histidine-rich protein | Histidine-rich protein PFHRP-II |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35156.49 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_500704 |
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| Residue: | 332 |
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| Sequence: | MVSFSKNKVLSAAVFASVLLLDNNNSAFNNNLCSKNAKGLNLNKRLLHETQAHVDDAHHA
HHVADAHHAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHA
ADAHHAHHAADAHHAHHAADAHHAHHAADAHHAHHAAYAHHAHHASDAHHAADAHHAAYA
HHAHHAADAHHAADAHHAAYAHHAHHAADAHHAADAHHATDAHHAHHAADAHHATDAHHA
ADAHHAADAHHATDAHHAADAHHATDAHHAADAHHAADAHHATDSHHAHHAADAHHAAAH
HATDAHHAAAHHATDAHHAAAHHEAATHCLRH
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| BDBM50003681 |
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| n/a |
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| Name | BDBM50003681 |
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| Synonyms: | CHEMBL468137 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H15ClN4O2S |
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| Mol. Mass. | 410.877 |
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| SMILES | Clc1ccc2c(NCCN3C(=S)N(C(=O)C3=O)c3ccccc3)ccnc2c1 |
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| Structure | 
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