| Reaction Details |
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 | Report a problem with these data |
| Target | Luciferin 4-monooxygenase |
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| Ligand | BDBM50004854 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_938513 (CHEMBL2327197) |
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| IC50 | 15±n/a nM |
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| Citation |  Poutiainen, PK; Palvimo, JJ; Hinkkanen, AE; Valkonen, A; Väisänen, TK; Laatikainen, R; Pulkkinen, JT Discovery of 5-benzyl-3-phenyl-4,5-dihydroisoxazoles and 5-benzyl-3-phenyl-1,4,2-dioxazoles as potent firefly luciferase inhibitors. J Med Chem56:1064-73 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Luciferin 4-monooxygenase |
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| Name: | Luciferin 4-monooxygenase |
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| Synonyms: | LUCI_PHOPY | Luciferase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60747.46 |
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| Organism: | Photinus pyralis |
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| Description: | ChEMBL_938513 |
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| Residue: | 550 |
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| Sequence: | MEDAKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMS
VRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNI
SQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYD
FVPESFDRDKTIALIMNSSGSTGLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSV
VPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTL
IDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPG
AVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHS
GDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGEL
PAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILI
KAKKGGKSKL
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| BDBM50004854 |
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| n/a |
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| Name | BDBM50004854 |
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| Synonyms: | CHEMBL2324046 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14ClNO |
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| Mol. Mass. | 271.741 |
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| SMILES | Clc1cccc(c1)C1=NOC(Cc2ccccc2)C1 |t:8| |
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| Structure | 
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