| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50005272 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1291356 (CHEMBL3117772) |
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| EC50 | >17000±n/a nM |
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| Citation |  Nanda, KK; Henze, DA; Della Penna, K; Desai, R; Leitl, M; Lemaire, W; White, RB; Yeh, S; Brouillette, JN; Hartman, GD; Bilodeau, MT; Trotter, BW Benzimidazole CB2 agonists: design, synthesis and SAR. Bioorg Med Chem Lett24:1218-21 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52868.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21554 |
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| Residue: | 472 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50005272 |
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| n/a |
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| Name | BDBM50005272 |
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| Synonyms: | CHEMBL3114522 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H20N4O |
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| Mol. Mass. | 380.4418 |
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| SMILES | CCn1c(nc2c(cccc12)-c1ccccc1)C(=O)NCc1ccc(cc1)C#N |
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| Structure | 
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