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TargetCaM kinase IV
LigandBDBM50001733
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1337316
IC50>10000±n/a nM
Citation Mahmoud KAKrug MWersig TSlynko ISchächtele CTotzke FSippl WHilgeroth A Discovery of 4-anilinoa-carbolines as novel Brk inhibitors. Bioorg Med Chem Lett 24:1948-51 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
CaM kinase IV
Name:CaM kinase IV
Synonyms:CAM kinase-GR | CAMK4 | CaMK IV | Calcium/calmodulin-dependent protein kinase type IV
Type:PROTEIN
Mol. Mass.:51919.87
Organism:Homo sapiens (Human)
Description:ChEMBL_1459854
Residue:473
Sequence:
MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIV
YRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLEL
VTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAP
LKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEP
FYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV
TGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHGSIQESHKASRDPS
PIQDGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKVQALEKVKGADINAEEAPKMVPKA
VEDGIKVADLELEEGLAEEKLKTVEEAAAPREGQGSSAVGFEVPQQDVILPEY
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  Blast E-value cutoff:
BDBM50001733
n/a
NameBDBM50001733
Synonyms:CHEMBL3133821
TypeSmall organic molecule
Emp. Form.C17H13N3O
Mol. Mass.275.3046
SMILESOc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1
Structure
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