| Reaction Details |
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 | Report a problem with these data |
| Target | Histone-lysine N-methyltransferase SETD7 |
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| Ligand | BDBM50001750 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1338134 (CHEMBL3242001) |
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| IC50 | 22500±n/a nM |
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| Citation |  Kashyap, S; Sandler, J; Peters, U; Martinez, EJ; Kapoor, TM Using 'biased-privileged' scaffolds to identify lysine methyltransferase inhibitors. Bioorg Med Chem22:2253-60 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone-lysine N-methyltransferase SETD7 |
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| Name: | Histone-lysine N-methyltransferase SETD7 |
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| Synonyms: | Histone-lysine N-methyltransferase SETD7 | KIAA1717 | KMT7 | SET domain-containing protein 7/9 (Set7/9) | SET7 | SET9 | SETD7 | SETD7_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 40691.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8WTS6 |
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| Residue: | 366 |
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| Sequence: | MDSDDEMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLE
GYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCW
IYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRP
HFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNT
VMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFT
PNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHSPPGKSGPEAPEWYQVELKAF
QATQQK
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| BDBM50001750 |
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| n/a |
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| Name | BDBM50001750 |
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| Synonyms: | CHEMBL3238424 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H21F3N2O2 |
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| Mol. Mass. | 486.4844 |
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| SMILES | OC(=O)c1cccc(NCc2cccc(c2)-n2ccc3c(cccc23)-c2ccc(cc2)C(F)(F)F)c1 |
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| Structure | 
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