| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM29278 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1337408 (CHEMBL3241553) |
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| Ki | 10.0±n/a nM |
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| Citation |  Moeker, J; Peat, TS; Bornaghi, LF; Vullo, D; Supuran, CT; Poulsen, SA Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes. J Med Chem57:3522-31 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM29278 |
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| n/a |
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| Name | BDBM29278 |
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| Synonyms: | CHEMBL310671 | Garantose | SAC | Saccharimide | Saccharin |
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| Type | Small organic molecule |
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| Emp. Form. | C7H5NO3S |
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| Mol. Mass. | 183.185 |
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| SMILES | O=C1NS(=O)(=O)c2ccccc12 |
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| Structure | 
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