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TargetProteasome subunit beta type-5
LigandBDBM50434764
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1334922 (CHEMBL3239238)
Ki 98±n/a nM
Citation Scarbaci, KTroiano, VMicale, NEttari, RTamborini, LDi Giovanni, CCerchia, CGrasso, SNovellino, ESchirmeister, TLavecchia, AZappalą, M Identification of a new series of amides as non-covalent proteasome inhibitors. Eur J Med Chem76:1-9 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Proteasome subunit beta type-5
Name:Proteasome subunit beta type-5
Synonyms:20S proteasome chymotrypsin-like | 26S proteosome | LMPX | MB1 | PSB5_HUMAN | PSMB5 | Proteasome Macropain subunit MB1 | Proteasome subunit beta type-1/beta type-5 | X
Type:Protein
Mol. Mass.:28480.96
Organism:Homo sapiens (Human)
Description:n/a
Residue:263
Sequence:
MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT
TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR
QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRI
SGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVRE
DGWIRVSSDNVADLHEKYSGSTP
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  Blast E-value cutoff:
BDBM50434764
n/a
NameBDBM50434764
Synonyms:CHEMBL2385814
TypeSmall organic molecule
Emp. Form.C18H24BN3O4
Mol. Mass.357.212
SMILESCC(C)C[C@H](NC(=O)Cn1ccc(Nc2ccccc2)cc1=O)B(O)O |r|
Structure
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