| Reaction Details |
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 | Report a problem with these data |
| Target | Protein arginine N-methyltransferase 6 |
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| Ligand | BDBM50388602 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1334938 (CHEMBL3239254) |
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| IC50 | 283000±n/a nM |
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| Citation |  Yan, L; Yan, C; Qian, K; Su, H; Kofsky-Wofford, SA; Lee, WC; Zhao, X; Ho, MC; Ivanov, I; Zheng, YG Diamidine compounds for selective inhibition of protein arginine methyltransferase 1. J Med Chem57:2611-22 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein arginine N-methyltransferase 6 |
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| Name: | Protein arginine N-methyltransferase 6 |
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| Synonyms: | ANM6_HUMAN | HRMT1L6 | Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6 | Histone-arginine N-methyltransferase PRMT6 | PRMT6 | Protein arginine methyltransferase 6 (PRMT6) |
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| Type: | Protein |
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| Mol. Mass.: | 41928.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 375 |
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| Sequence: | MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALERPRRTKRERDQLYYECYSDVSVHEEM
IADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQA
REVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKE
GGLLLPASAELFIAPISDQMLEWRLGFWSQVKQHYGVDMSCLEGFATRCLMGHSEIVVQG
LSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAIWFQVTFPGGE
SEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNPRRLRVLLRYK
VGDQEEKTKDFAMED
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| BDBM50388602 |
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| n/a |
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| Name | BDBM50388602 |
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| Synonyms: | FURAMIDINE |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16N4O |
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| Mol. Mass. | 304.3458 |
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| SMILES | NC(=N)c1ccc(cc1)-c1ccc(o1)-c1ccc(cc1)C(N)=N |w:1.0,20.23| |
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| Structure | 
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