| Reaction Details |
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 | Report a problem with these data |
| Target | Fe(3+)-Zn(2+) purple acid phosphatase |
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| Ligand | BDBM50162816 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1337988 (CHEMBL3241395) |
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| Ki | 140000±n/a nM |
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| Citation |  McGeary, RP; Schenk, G; Guddat, LW The applications of binuclear metallohydrolases in medicine: recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-ß-lactamases and arginases. Eur J Med Chem76:132-44 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Fe(3+)-Zn(2+) purple acid phosphatase |
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| Name: | Fe(3+)-Zn(2+) purple acid phosphatase |
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| Synonyms: | Iron(III)-zinc(II) purple acid phosphatase | PAP | PPAF_PHAVU |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52875.57 |
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| Organism: | Phaseolus vulgaris |
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| Description: | ChEMBL_560427 |
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| Residue: | 459 |
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| Sequence: | MGVVKGLLALALVLNVVVVSNGGKSSNFVRKTNKNRDMPLDSDVFRVPPGYNAPQQVHIT
QGDLVGRAMIISWVTMDEPGSSAVRYWSEKNGRKRIAKGKMSTYRFFNYSSGFIHHTTIR
KLKYNTKYYYEVGLRNTTRRFSFITPPQTGLDVPYTFGLIGDLGQSFDSNTTLSHYELSP
KKGQTVLFVGDLSYADRYPNHDNVRWDTWGRFTERSVAYQPWIWTAGNHEIEFAPEINET
EPFKPFSYRYHVPYEASQSTSPFWYSIKRASAHIIVLSSYSAYGRGTPQYTWLKKELRKV
KRSETPWLIVLMHSPLYNSYNHHFMEGEAMRTKFEAWFVKYKVDVVFAGHVHAYERSERV
SNIAYKITNGLCTPVKDQSAPVYITIGDAGNYGVIDSNMIQPQPEYSAFREASFGHGMFD
IKNRTHAHFSWNRNQDGVAVEADSVWFFNRHWYPVDDST
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| BDBM50162816 |
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| n/a |
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| Name | BDBM50162816 |
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| Synonyms: | CHEMBL180570 | Medronic acid | Methylene diphsphonate | Phosphonomethyl-phosphonic acid | methylenediphosphonic acid |
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| Type | Small organic molecule |
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| Emp. Form. | CH6O6P2 |
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| Mol. Mass. | 176.0023 |
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| SMILES | OP(O)(=O)CP(O)(O)=O |
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| Structure | 
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