| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase N catalytic chain |
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| Ligand | BDBM50008273 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1339191 (CHEMBL3243354) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Brink, M; Dahlén, A; Olsson, T; Polla, M; Svensson, T Design and synthesis of conformationally restricted inhibitors of active thrombin activatable fibrinolysis inhibitor (TAFIa). Bioorg Med Chem22:2261-8 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase N catalytic chain |
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| Name: | Carboxypeptidase N catalytic chain |
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| Synonyms: | ACBP | Anaphylatoxin inactivator | Arginine carboxypeptidase | CBPN_HUMAN | CPN | CPN1 | Carboxypeptidase N catalytic chain | Carboxypeptidase N polypeptide 1 | Carboxypeptidase N small subunit | Carboxypeptidase N, catalytic subunit | Kininase-1 | Lysine carboxypeptidase | Plasma carboxypeptidase B | SCPN | Serum carboxypeptidase N |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52293.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1496379 |
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| Residue: | 458 |
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| Sequence: | MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHL
YVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQD
TRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN
HHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRT
ASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHT
NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS
VSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIP
QVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
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| BDBM50008273 |
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| n/a |
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| Name | BDBM50008273 |
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| Synonyms: | CHEMBL3235134 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H27N3O2 |
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| Mol. Mass. | 305.4152 |
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| SMILES | NCCC[C@]1(CCc2c(C1)ncn2C1CCCCC1)C(O)=O |r| |
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| Structure | 
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