Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Carboxypeptidase N catalytic chain | ||
| Ligand | BDBM50008275 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1339191 (CHEMBL3243354) | ||
| IC50 | >1000000±n/a nM | ||
| Citation |  Brink, M; Dahlén, A; Olsson, T; Polla, M; Svensson, T Design and synthesis of conformationally restricted inhibitors of active thrombin activatable fibrinolysis inhibitor (TAFIa). Bioorg Med Chem22:2261-8 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Carboxypeptidase N catalytic chain | |||
| Name: | Carboxypeptidase N catalytic chain | ||
| Synonyms: | ACBP | Anaphylatoxin inactivator | Arginine carboxypeptidase | CBPN_HUMAN | CPN | CPN1 | Carboxypeptidase N catalytic chain | Carboxypeptidase N polypeptide 1 | Carboxypeptidase N small subunit | Carboxypeptidase N, catalytic subunit | Kininase-1 | Lysine carboxypeptidase | Plasma carboxypeptidase B | SCPN | Serum carboxypeptidase N | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 52293.66 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1496379 | ||
| Residue: | 458 | ||
| Sequence: |
| ||
| BDBM50008275 | |||
| n/a | |||
| Name | BDBM50008275 | ||
| Synonyms: | CHEMBL3235136 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H41N3O2 | ||
| Mol. Mass. | 415.6119 | ||
| SMILES | NCCCC1(CCc2c(C1)ncn2CCC1CCC(CC1)C1CCCCC1)C(O)=O |(12.03,-18.01,;11.64,-19.5,;10.15,-19.91,;9.76,-21.4,;8.28,-21.8,;8.28,-20.26,;6.95,-19.48,;5.61,-20.25,;5.62,-21.8,;6.95,-22.56,;4.15,-22.29,;3.24,-21.04,;4.14,-19.78,;3.66,-18.32,;4.68,-17.17,;4.2,-15.71,;5.22,-14.56,;4.74,-13.1,;3.23,-12.78,;2.2,-13.93,;2.68,-15.4,;2.75,-11.32,;3.78,-10.18,;3.31,-8.72,;1.8,-8.39,;.77,-9.54,;1.25,-11.01,;9.04,-23.13,;8.26,-24.46,;10.58,-23.14,)| | ||
| Structure | 
| ||