Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMu-type opioid receptor
LigandBDBM50009269
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1335006 (CHEMBL3239393)
IC50 4.6±n/a nM
Citation Cai, JSong, BCai, YMa, YLam, ALMagiera, JSekar, SWyse, BDAmbo, ASasaki, YLazarus, LHSmith, MTLi, T Endomorphin analogues with mixedµ-opioid (MOP) receptor agonism/d-opioid (DOP) receptor antagonism and lackingß-arrestin2 recruitment activity. Bioorg Med Chem22:2208-19 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:Enzyme Catalytic Domain
Mol. Mass.:11165.58
Organism:GUINEA PIG
Description:P97266
Residue:98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50009269
n/a
NameBDBM50009269
Synonyms:CHEMBL3233198
TypeSmall organic molecule
Emp. Form.C29H34N4O4
Mol. Mass.502.6047
SMILESCc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cccc2ccccc12)C(N)=O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: