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TargetChromobox protein homolog 7
LigandBDBM50009469
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1336411 (CHEMBL3242415)
IC50 8800±n/a nM
Citation Simhadri, CDaze, KDDouglas, SFQuon, TTDev, AGignac, MCPeng, FHeller, MBoulanger, MJWulff, JEHof, F Chromodomain antagonists that target the polycomb-group methyllysine reader protein chromobox homolog 7 (CBX7). J Med Chem57:2874-83 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Chromobox protein homolog 7
Name:Chromobox protein homolog 7
Synonyms:CBX7 | CBX7_HUMAN | Chromobox protein homolog 7 | Chromobox protein homolog 7 (CBX7)
Type:Protein
Mol. Mass.:28351.76
Organism:Homo sapiens (Human)
Description:n/a
Residue:251
Sequence:
MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK
EERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVKA
GAPELVDKGPLVPTLPFPLRKPRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPPAP
DVLQAAGEWEPAAQPPEEEADADLAEGPPPWTPALPSSEVTVTDITANSITVTFREAQAA
EGFFRDRSGKF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50009469
n/a
NameBDBM50009469
Synonyms:CHEMBL3234151
TypeSmall organic molecule
Emp. Form.C35H58N7O7
Mol. Mass.688.8772
SMILESC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)N[C@@H](CO)C(N)=O |r|
Structure
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