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TargetChromobox protein homolog 8
LigandBDBM50009526
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1336413
Kd 15000±n/a nM
Citation Simhadri CDaze KDDouglas SFQuon TTDev AGignac MCPeng FHeller MBoulanger MJWulff JEHof F Chromodomain antagonists that target the polycomb-group methyllysine reader protein chromobox homolog 7 (CBX7). J Med Chem 57:2874-83 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Chromobox protein homolog 8
Name:Chromobox protein homolog 8
Synonyms:CBX8 | PC3 | Pc3 | Polycomb 3 homolog | RC1 | Rectachrome 1 | hPc3
Type:PROTEIN
Mol. Mass.:43415.86
Organism:Homo sapiens (Human)
Description:ChEMBL_108272
Residue:389
Sequence:
MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEER
EREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQDLASTSRA
REGLRNMGLSPPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERER
GTSRVDDKPSSPGDSSKKRGPKPRKELPDPSQRPLGEPSAGLGEYLKGRKLDDTPSGAGK
FPAGHSVIQLARRQDSDLVQCGVTSPSSAEATGKLAVDTFPARVIKHRAAFLEAKGQGAL
DPNGTRVRHGSGPPSSGGGLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEK
VVVTDVTSNFLTVTIKESNTDQGFFKEKR
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  Blast E-value cutoff:
BDBM50009526
n/a
NameBDBM50009526
Synonyms:CHEMBL3234440
TypeSmall organic molecule
Emp. Form.C30H50N5O6
Mol. Mass.576.7474
SMILESC[C@H](NC(=O)Cc1ccccc1)C(=O)N[C@@H](C1CCCC1)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)NC(CO)CO |r|
Structure
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