| Reaction Details |
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 | Report a problem with these data |
| Target | Histidine decarboxylase |
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| Ligand | BDBM50010139 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1344422 (CHEMBL3258372) |
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| Ki | 1800±n/a nM |
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| Citation |  Kelley, JL; Miller, CA; White, HL Inhibition of histidine decarboxylase. Derivatives of histidine. J Med Chem20:506-9 (1977) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histidine decarboxylase |
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| Name: | Histidine decarboxylase |
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| Synonyms: | DCHS_RAT | Hdc |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73643.55 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_108298 |
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| Residue: | 656 |
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| Sequence: | MMEPSEYHEYQARGKEMVDYICQYLSTVRERQVTPNVKPGYLRAQIPSSAPEEPDSWDSI
FGDIEQIIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEM
NIMDWLAKMLGLPDFFLHHHPSSQGGGVLQRTVSESTLIALLAARKNKILEMKAHEPNAD
ESSLNARLVAYASDQAHSSVEKAGLISLVKIKFLPVDDNFSLRGEALQKAIEEDKQQGLV
PVFVCATLGTTGVCAFDKLSELGPICAREGLWLHVDAAYAGTAFLRPELRGFLKGIEYAD
SFTFNPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHANSGVATDFMHWQIPLSRRF
RSIKLWFVIRSFGVKNLQAHVRHGTDMAKYFESLVRSDPVFEIPAERHLGLVVFRLKGPN
CLTESVLKEIAKTGQVFLIPATIQDKLIIRFTVTSQFTTKDDILRDWNLIREAANLVLSQ
HCTSQPSPRAKNLIPPPVTRDSKDLTNGLSLESVNEGGDDPVQVRKIFRLPGDSLETTMD
PFDDCFSEEASDTTKHKLSSFLFSYLSVQNKKKTMRSLSCNSMPMSAQKSPPPDASVKHG
GFFRARIFSGFPEEMMMMKKGGFKKLIKFYSVPSFPECSSQCGTLQLPCCPLQAMV
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| BDBM50010139 |
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| n/a |
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| Name | BDBM50010139 |
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| Synonyms: | CHEMBL54664 | L-Histidine Methyl Ester |
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| Type | Small organic molecule |
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| Emp. Form. | C7H11N3O2 |
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| Mol. Mass. | 169.1811 |
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| SMILES | COC(=O)[C@@H](N)Cc1c[nH]cn1 |r| |
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| Structure | 
|
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