Reaction Details |
| Report a problem with these data |
Target | Aminopeptidase B |
---|
Ligand | BDBM23971 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_1344423 (CHEMBL3258373) |
---|
IC50 | 160±n/a nM |
---|
Citation | Nishizawa, R; Saino, T; Takita, T; Suda, H; Aoyagi, T Synthesis and structure-activity relationships of bestatin analogues, inhibitors of aminopeptidase B. J Med Chem20:510-5 (1977) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Aminopeptidase B |
---|
Name: | Aminopeptidase B |
Synonyms: | AMPB_RAT | Ap-B | Arginine aminopeptidase | Arginyl aminopeptidase | Cytosol aminopeptidase IV | Rnpep |
Type: | PROTEIN |
Mol. Mass.: | 72609.93 |
Organism: | Rattus norvegicus |
Description: | ChEMBL_1344423 |
Residue: | 650 |
Sequence: | MESSGPSSCHSAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLN
GKATLELRCLLPEGASELRLDSHSCLEVMAATLLRGQPGDQQQLTEPVPFHTQPFSHYGQ
ALCVVFPKPCCAAERFRLELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFP
CFDTPAVKCTYSALVEVPDGFTAVMSASTWERRGPNKFFFQMSQPIPSYLIALAIGDLAS
AEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGM
ENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRIST
ILFGAAYTCLEAATGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCF
VSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFN
RWLNTPGWPPYLPDLSPGDSLMKPAEELAELWAASEPDMQAIEAVAISTWKTYQLVYFLD
KILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDHQEEFWKVKDFLQSQGK
QKYTLPLYHAMMGGSEMARTLAKETFSATASQLHSNVVNYVQQILAPKGS
|
|
|
BDBM23971 |
---|
n/a |
---|
Name | BDBM23971 |
Synonyms: | (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid | Bestatin | CHEMBL29292 | Ubenimex |
Type | Small organic molecule |
Emp. Form. | C16H24N2O4 |
Mol. Mass. | 308.3728 |
SMILES | CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O |
Structure |
|