| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50011237 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1351817 (CHEMBL3271323) |
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| Ki | 12±n/a nM |
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| Citation |  Abdel-Magid, AF Selective 5-HT Receptor Modulators May Deliver Focused Targeting with Fewer Adverse Effects. ACS Med Chem Lett5:284-5 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-Hydroxytryptamine receptor 7 (5-HT7) | 5-hydroxytryptamine receptor 7 | 5-hydroxytryptamine receptor 7 (5-HT-7) | 5HT7R_RAT | Adrenergic Alpha | GPRFO | Htr7 | Serotonin (5-HT) receptor | Serotonin Receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 49852.62 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Rat cloned 5-HT7R. |
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| Residue: | 448 |
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| Sequence: | MMDVNSSGRPDLYGHLRSLILPEVGRGLQDLSPDGGAHPVVSSWMPHLLSGFLEVTASPA
PTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSN
YLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVIS
IDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDF
GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVQPESVISLNGVVKLQK
EVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTS
CSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHE
ALKLAERPERSEFVLQNSDHCGKKGHDT
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| BDBM50011237 |
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| n/a |
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| Name | BDBM50011237 |
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| Synonyms: | CHEMBL3260334 | US9981909, Example 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H15BrClNO2 |
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| Mol. Mass. | 368.653 |
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| SMILES | Clc1cccc(COc2ccc(Br)cc2OC2CNC2)c1 |
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| Structure | 
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