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TargetG-protein coupled receptor 183
LigandBDBM50011578
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1351308 (CHEMBL3266157)
IC50 17±n/a nM
Citation Gessier, FPreuss, IYin, HRosenkilde, MMLaurent, SEndres, RChen, YAMarsilje, THSeuwen, KNguyen, DGSailer, AW Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor. J Med Chem57:3358-68 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
G-protein coupled receptor 183
Name:G-protein coupled receptor 183
Synonyms:EBI2 | GP183_HUMAN | GPR183
Type:PROTEIN
Mol. Mass.:41245.79
Organism:Homo sapiens (Human)
Description:ChEMBL_108311
Residue:361
Sequence:
MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNR
KKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVN
FMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERIT
CMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNK
KALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFN
CCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNG
K
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BDBM50011578
n/a
NameBDBM50011578
Synonyms:CHEMBL3262890
TypeSmall organic molecule
Emp. Form.C23H24N2O5
Mol. Mass.408.4471
SMILESCOC(=O)c1ccc(cc1)C(=O)N1CCN(CC1)C(=O)\C=C\c1ccc(OC)cc1
Structure
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