| Reaction Details |
|---|
 | Report a problem with these data |
| Target | G-protein coupled receptor 183 |
|---|
| Ligand | BDBM50011717 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1351307 (CHEMBL3266156) |
|---|
| IC50 | 83±n/a nM |
|---|
| Citation |  Gessier, F; Preuss, I; Yin, H; Rosenkilde, MM; Laurent, S; Endres, R; Chen, YA; Marsilje, TH; Seuwen, K; Nguyen, DG; Sailer, AW Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor. J Med Chem57:3358-68 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| G-protein coupled receptor 183 |
|---|
| Name: | G-protein coupled receptor 183 |
|---|
| Synonyms: | EBI2 | GP183_HUMAN | GPR183 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 41245.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_108311 |
|---|
| Residue: | 361 |
|---|
| Sequence: | MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNR
KKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVN
FMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERIT
CMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNK
KALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFN
CCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNG
K
|
|
|
|---|
| BDBM50011717 |
|---|
| n/a |
|---|
| Name | BDBM50011717 |
|---|
| Synonyms: | CHEMBL3262876 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H24N2O3 |
|---|
| Mol. Mass. | 388.459 |
|---|
| SMILES | O=C(COc1ccc2ccccc2c1)N1CCN(CC1)C(=O)Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
