| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 183 |
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| Ligand | BDBM50011716 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1352279 (CHEMBL3268997) |
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| IC50 | 8.5±n/a nM |
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| Citation |  Gessier, F; Preuss, I; Yin, H; Rosenkilde, MM; Laurent, S; Endres, R; Chen, YA; Marsilje, TH; Seuwen, K; Nguyen, DG; Sailer, AW Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor. J Med Chem57:3358-68 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 183 |
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| Name: | G-protein coupled receptor 183 |
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| Synonyms: | EBI2 | GP183_HUMAN | GPR183 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41245.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108311 |
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| Residue: | 361 |
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| Sequence: | MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNR
KKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVN
FMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERIT
CMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNK
KALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFN
CCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNG
K
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| BDBM50011716 |
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| n/a |
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| Name | BDBM50011716 |
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| Synonyms: | CHEMBL3262896 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21BrN2O3 |
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| Mol. Mass. | 429.307 |
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| SMILES | COc1ccc(cc1)C(=O)N1CCN(CC1)C(=O)\C=C\c1ccc(Br)cc1 |
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| Structure | 
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