| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM71581 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1352796 (CHEMBL3268196) |
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| IC50 | >32000±n/a nM |
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| Citation |  Urbano, M; Guerrero, M; Rosen, H; Roberts, E Antagonists of the kappa opioid receptor. Bioorg Med Chem Lett24:2021-32 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM71581 |
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| n/a |
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| Name | BDBM71581 |
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| Synonyms: | KSC-5-280C | KUC104162N | N-[2-[(4-bromobenzyl)-isopropyl-amino]ethyl]-4-[(tosylamino)methyl]benzamide | N-[2-[(4-bromophenyl)methyl-propan-2-yl-amino]ethyl]-4-[[(4-methylphenyl)sulfonylamino]methyl]benzamide | N-[2-[(4-bromophenyl)methyl-propan-2-ylamino]ethyl]-4-[[(4-methylphenyl)sulfonylamino]methyl]benzamide | cid_44620907 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H32BrN3O3S |
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| Mol. Mass. | 558.53 |
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| SMILES | CC(C)N(CCNC(=O)c1ccc(CNS(=O)(=O)c2ccc(C)cc2)cc1)Cc1ccc(Br)cc1 |
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| Structure | 
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