Reaction Details |
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Target | P2Y purinoceptor 2 |
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Ligand | BDBM50012976 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1351702 (CHEMBL3270102) |
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EC50 | 457±n/a nM |
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Citation | Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA 4-Alkyloxyimino derivatives of uridine-5'-triphosphate: distal modification of potent agonists as a strategy for molecular probes of P2Y2, P2Y4, and P2Y6 receptors. J Med Chem57:3874-83 (2014) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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P2Y purinoceptor 2 |
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Name: | P2Y purinoceptor 2 |
Synonyms: | ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2 |
Type: | PROTEIN |
Mol. Mass.: | 42299.21 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1455361 |
Residue: | 377 |
Sequence: | MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC
RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS
ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR
VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK
RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC
LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR
RTESTPAGSENTKDIRL
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BDBM50012976 |
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n/a |
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Name | BDBM50012976 |
Synonyms: | CHEMBL3261367 |
Type | Small organic molecule |
Emp. Form. | C18H25N4O17P3 |
Mol. Mass. | 662.329 |
SMILES | O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2cccc(c2)[N+]([O-])=O)[nH]c1=O |r| |
Structure |
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