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TargetP2Y purinoceptor 4
LigandBDBM50012958
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1351703 (CHEMBL3270103)
EC50 100±n/a nM
Citation Jayasekara, PSBarrett, MOBall, CBBrown, KAHammes, EBalasubramanian, RHarden, TKJacobson, KA 4-Alkyloxyimino derivatives of uridine-5'-triphosphate: distal modification of potent agonists as a strategy for molecular probes of P2Y2, P2Y4, and P2Y6 receptors. J Med Chem57:3874-83 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
P2Y purinoceptor 4
Name:P2Y purinoceptor 4
Synonyms:NRU | P2P | P2RY4 | P2RY4_HUMAN | P2Y purinoceptor 4 | P2Y4 | Pyrimidinergic receptor P2Y4 | UNR | Uridine nucleotide receptor
Type:PROTEIN
Mol. Mass.:40977.17
Organism:Homo sapiens (Human)
Description:ChEMBL_751027
Residue:365
Sequence:
MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLF
IFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLY
CSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKG
TTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSR
LRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSC
LDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTP
RADRL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50012958
n/a
NameBDBM50012958
Synonyms:CHEMBL3261362
TypeSmall organic molecule
Emp. Form.C18H25FN3O15P3
Mol. Mass.635.3219
SMILESO[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2cccc(F)c2)[nH]c1=O |r|
Structure
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