Reaction Details |
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Target | P2Y purinoceptor 4 |
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Ligand | BDBM50012975 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1351703 (CHEMBL3270103) |
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EC50 | 91±n/a nM |
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Citation | Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA 4-Alkyloxyimino derivatives of uridine-5'-triphosphate: distal modification of potent agonists as a strategy for molecular probes of P2Y2, P2Y4, and P2Y6 receptors. J Med Chem57:3874-83 (2014) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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P2Y purinoceptor 4 |
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Name: | P2Y purinoceptor 4 |
Synonyms: | NRU | P2P | P2RY4 | P2RY4_HUMAN | P2Y purinoceptor 4 | P2Y4 | Pyrimidinergic receptor P2Y4 | UNR | Uridine nucleotide receptor |
Type: | PROTEIN |
Mol. Mass.: | 40977.17 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_751027 |
Residue: | 365 |
Sequence: | MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLF
IFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLY
CSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKG
TTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSR
LRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSC
LDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTP
RADRL
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BDBM50012975 |
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n/a |
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Name | BDBM50012975 |
Synonyms: | CHEMBL3261366 |
Type | Small organic molecule |
Emp. Form. | C18H25IN3O15P3 |
Mol. Mass. | 743.228 |
SMILES | O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2ccc(I)cc2)[nH]c1=O |r| |
Structure |
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