| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 4 |
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| Ligand | BDBM50012978 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1351703 (CHEMBL3270103) |
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| EC50 | 23±n/a nM |
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| Citation |  Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA 4-Alkyloxyimino derivatives of uridine-5'-triphosphate: distal modification of potent agonists as a strategy for molecular probes of P2Y2, P2Y4, and P2Y6 receptors. J Med Chem57:3874-83 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 4 |
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| Name: | P2Y purinoceptor 4 |
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| Synonyms: | NRU | P2P | P2RY4 | P2RY4_HUMAN | P2Y purinoceptor 4 | P2Y4 | Pyrimidinergic receptor P2Y4 | UNR | Uridine nucleotide receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40977.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_751027 |
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| Residue: | 365 |
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| Sequence: | MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLF
IFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLY
CSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKG
TTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSR
LRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSC
LDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTP
RADRL
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| BDBM50012978 |
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| n/a |
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| Name | BDBM50012978 |
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| Synonyms: | CHEMBL3261369 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H28N3O16P3 |
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| Mol. Mass. | 647.3574 |
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| SMILES | COc1ccc(CCCO\N=c2\ccn([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c(=O)[nH]2)cc1 |r| |
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| Structure | 
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