| Reaction Details |
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 | Report a problem with these data |
| Target | Macrophage migration inhibitory factor |
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| Ligand | BDBM50013032 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1351719 (CHEMBL3270119) |
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| Ki | 348±n/a nM |
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| Citation |  Xu, L; Zhang, Y; Zheng, L; Qiao, C; Li, Y; Li, D; Zhen, X; Hou, T Discovery of novel inhibitors targeting the macrophage migration inhibitory factor via structure-based virtual screening and bioassays. J Med Chem57:3737-45 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Macrophage migration inhibitory factor |
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| Name: | Macrophage migration inhibitory factor |
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| Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
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| Type: | Enzyme |
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| Mol. Mass.: | 12478.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14174 |
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| Residue: | 115 |
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| Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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| BDBM50013032 |
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| n/a |
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| Name | BDBM50013032 |
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| Synonyms: | CHEMBL1604170 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H16N2O3S |
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| Mol. Mass. | 376.428 |
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| SMILES | OC(=O)c1cccc(NC(=S)NC(=O)c2ccc(cc2)-c2ccccc2)c1 |
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| Structure | 
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