| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D-alanyl-D-alanine dipeptidase |
|---|
| Ligand | BDBM50014161 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1350288 (CHEMBL3267626) |
|---|
| Ki | 2740±n/a nM |
|---|
| Citation |  Muthyala, R; Rastogi, N; Shin, WS; Peterson, ML; Sham, YY Cell permeable vanX inhibitors as vancomycin re-sensitizing agents. Bioorg Med Chem Lett24:2535-8 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D-alanyl-D-alanine dipeptidase |
|---|
| Name: | D-alanyl-D-alanine dipeptidase |
|---|
| Synonyms: | D-Ala-D-Ala dipeptidase | VANX_ENTFC | Vancomycin B-type resistance protein vanX | vanX |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 23377.40 |
|---|
| Organism: | Enterococcus faecium |
|---|
| Description: | ChEMBL_1350288 |
|---|
| Residue: | 202 |
|---|
| Sequence: | MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTYELAESLLKAKELAATQ
GYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRTEMISKGYVASKSSHSRGS
AIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEAQNRRRLRSIMENSGFEAYSL
EWWHYVLRDEPYPNSYFDFPVK
|
|
|
|---|
| BDBM50014161 |
|---|
| n/a |
|---|
| Name | BDBM50014161 |
|---|
| Synonyms: | CHEMBL3260858 | US11491146, Compound 5 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H12N2O4S |
|---|
| Mol. Mass. | 304.321 |
|---|
| SMILES | OC(=O)[C@H](NC(=O)c1cccc(=S)n1O)c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
