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TargetDelta-aminolevulinic acid dehydratase
LigandBDBM50017185
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1365593
IC50 500000±n/a nM
Citation Lentz CSHalls VSHannam JSStrassel SLawrence SHJaffe EKFamulok MHoerauf APfarr KM wALADin benzimidazoles differentially modulate the function of porphobilinogen synthase orthologs. J Med Chem 57:2498-510 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Delta-aminolevulinic acid dehydratase
Name:Delta-aminolevulinic acid dehydratase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:36671.06
Organism:Wolbachia sp. subsp. Brugia malayi (strain TRS)
Description:ChEMBL_108383
Residue:331
Sequence:
MMFNFPNTRLRRRRSSKWVRNLTSESALSVNDLIFPLFVHDREETTELVSSLPGMKCYSI
DGLVSIAQEAEDLGINAVAIFPVVDSKLKSENAEEAYNSDNLICKAIRAIKLKVPGIGII
ADVALDPYTTHGHDGILKSNQIDVENDKTVSILCKQALALAKAGCNIVASSDMMDGRVGR
IRKVLDDNNLQDVSILSYAVKYCSSFYAPFRQIVGSCVSSNSIDKSGYQMDYRNAREAIC
EIEMDLNEGADFIMVKPGMPYLDIIKMASDEFNFPIFAYQVSGEYAMIKAATNNGWLDYD
KVIYESLVGFKRAGASAIFTYAALDVAKNLR
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  Blast E-value cutoff:
BDBM50017185
n/a
NameBDBM50017185
Synonyms:CHEMBL3287361
TypeSmall organic molecule
Emp. Form.C23H18F3N3O3S
Mol. Mass.473.468
SMILESOC(=O)c1cccc2n(Cc3cccc(c3)C(F)(F)F)c(CCNC(=O)c3cccs3)nc12
Structure
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