Ki Summary

Reaction Details

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Target

Fibroblast growth factor 4

Ligand

BDBM50017345

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_1363177 (CHEMBL3293892)

25000000±n/a nM

Citation

Roy, S; El Hadri, A; Richard, S; Denis, F; Holte, K; Duffner, J; Yu, F; Galcheva-Gargova, Z; Capila, I; Schultes, B; Petitou, M; Kaundinya, GV Synthesis and biological evaluation of a unique heparin mimetic hexasaccharide for structure-activity relationship studies. J Med Chem57:4511-20 (2014) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Fibroblast growth factor 4

Name:

Fibroblast growth factor 4

Synonyms:

FGF-4 | FGF4 | FGF4_HUMAN | HBGF-4 | HST | HST-1 | HSTF-1 | HSTF1 | Heparin secretory-transforming protein 1 | Heparin-binding growth factor 4 | KS3 | Transforming protein KS3

Type:

PROTEIN

Mol. Mass.:

22057.91

Organism:

Homo sapiens (Human)

Description:

ChEMBL_108374

Residue:

206

Sequence:

MSGPGTAAVALLPAVLLALLAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPV
AAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSP
VERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPGMFIA
LSKNGKTKKGNRVSPTMKVTHFLPRL

BDBM50017345

n/a

Name

BDBM50017345

Synonyms:

CHEMBL3288260

Type

Small organic molecule

Emp. Form.

C45H64N3Na9O51S6

Mol. Mass.

1862.277

SMILES

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[H][C@]1(O[C@@H]2O[C@@H](C([O-])=O)[C@@]([H])(O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@]([H])(O[C@@H]4O[C@@H](C([O-])=O)[C@@]([H])(O[C@H]5O[C@H](COS([O-])(=O)=O)[C@@]([H])(O[C@@H]6O[C@H]([C@@H](O)[C@H](O)[C@H]6OS([O-])(=O)=O)C([O-])=O)[C@H](O)[C@H]5NC(C)=O)[C@H](O)[C@H]4OS([O-])(=O)=O)[C@H](O)[C@H]3NS([O-])(=O)=O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](NC(C)=O)[C@@H](OCCCCC)O[C@@H]1COS([O-])(=O)=O |r|

Structure