| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
|---|
| Ligand | BDBM86453 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1362121 (CHEMBL3294893) |
|---|
| EC50 | 1.6±n/a nM |
|---|
| Citation |  Jacobsen, JR; Aggen, JB; Church, TJ; Klein, U; Pfeiffer, JW; Pulido-Rios, TM; Thomas, GR; Yu, C; Moran, EJ Multivalent design of long-actingß(2)-adrenoceptor agonists incorporating biarylamines. Bioorg Med Chem Lett24:2625-30 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-2 adrenergic receptor |
|---|
| Name: | Beta-2 adrenergic receptor |
|---|
| Synonyms: | ADRB2_CAVPO | Adrb2 | adrenergic Beta2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 46993.24 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4 |
|---|
| Residue: | 418 |
|---|
| Sequence: | MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKD
AINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRF
HTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNG
KTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
|
|
|
|---|
| BDBM86453 |
|---|
| n/a |
|---|
| Name | BDBM86453 |
|---|
| Synonyms: | CAS_73573-87-2 | Formoterol | NSC_3083544 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H24N2O4 |
|---|
| Mol. Mass. | 344.4049 |
|---|
| SMILES | COc1ccc(CC(C)NCC(O)c2ccc(O)c(NC=O)c2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
