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TargetBeta-1 adrenergic receptor
LigandBDBM50018609
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1362119
Ki 12589±n/a nM
Citation Jacobsen JRAggen JBChurch TJKlein UPfeiffer JWPulido-Rios TMThomas GRYu CMoran EJ Multivalent design of long-acting▀(2)-adrenoceptor agonists incorporating biarylamines. Bioorg Med Chem Lett 24:2625-30 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-1 adrenergic receptor
Name:Adrenergic receptor
Synonyms:B1AR | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:51338.40
Organism:Homo sapiens (Human)
Description:n/a
Residue:477
Sequence:
MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP
LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV
FFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHATHGDRPRASGCLARPGP
PPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
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  Blast E-value cutoff:
BDBM50018609
n/a
NameBDBM50018609
Synonyms:CHEMBL3290990
TypeSmall organic molecule
Emp. Form.C24H28N2O4
Mol. Mass.408.4901
SMILESCOc1cccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)c1
Structure
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