| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50018997 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1365294 (CHEMBL3292388) |
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| EC50 | 2.5±n/a nM |
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| Citation |  Nagase, H; Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Nemoto, T; Gouda, H; Hirono, S; Fujii, H Design and synthesis of quinolinopropellane derivatives with selectived opioid receptor agonism. Bioorg Med Chem Lett24:2851-4 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50018997 |
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| n/a |
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| Name | BDBM50018997 |
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| Synonyms: | CHEMBL3287467 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H28N2O |
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| Mol. Mass. | 396.524 |
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| SMILES | Oc1ccc2C[C@@]34CN(CC5CC5)CC[C@@]3(Cc3nc5ccccc5cc3C4)c2c1 |r| |
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| Structure | 
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