| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM50377964 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1362503 (CHEMBL3293104) |
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| Ki | 0.680000±n/a nM |
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| Citation |  Yamashita, Y; Tanaka, K; Asano, T; Yamakawa, N; Kobayashi, D; Ishihara, T; Hanaya, K; Shoji, M; Sugai, T; Wada, M; Mashimo, T; Fukunishi, Y; Mizushima, T Synthesis and biological comparison of enantiomers of mepenzolate bromide, a muscarinic receptor antagonist with bronchodilatory and anti-inflammatory activities. Bioorg Med Chem22:3488-97 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_HUMAN | CHRM2 | Cholinergic, muscarinic M2 | Muscarinic acetylcholine receptor M2 and M4 | Muscarinic acetylcholine receptor M2 and M5 | RecName: Full=Muscarinic acetylcholine receptor M2 |
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| Type: | GPCR |
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| Mol. Mass.: | 51730.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08172 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM50377964 |
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| n/a |
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| Name | BDBM50377964 |
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| Synonyms: | Cantil | Glycophenylate | MEPENZOLATE BROMIDE | Mepenzolate |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26NO3 |
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| Mol. Mass. | 340.4355 |
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| SMILES | C[N+]1(C)CCCC(C1)OC(=O)C(O)(c1ccccc1)c1ccccc1 |
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| Structure | 
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