| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 11 |
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| Ligand | BDBM50019292 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1362532 (CHEMBL3293346) |
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| EC50 | 900±n/a nM |
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| Citation |  Nadel, Y; Lecka, J; Gilad, Y; Ben-David, G; Förster, D; Reiser, G; Kenigsberg, S; Camden, J; Weisman, GA; Senderowitz, H; Sévigny, J; Fischer, B Highly potent and selective ectonucleotide pyrophosphatase/phosphodiesterase I inhibitors based on an adenosine 5'-(a or¿)-thio-(a,ß- orß,¿)-methylenetriphosphate scaffold. J Med Chem57:4677-91 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 11 |
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| Name: | P2Y purinoceptor 11 |
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| Synonyms: | P2RY11 | P2Y purinoceptor 11 | P2Y11 | P2Y11_HUMAN | Purinergic receptor P2Y11 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40366.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1362532 |
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| Residue: | 374 |
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| Sequence: | MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRP
WHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFI
TCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNC
SVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTV
AEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPY
VGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATA
APKPSEPQSRELSQ
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| BDBM50019292 |
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| n/a |
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| Name | BDBM50019292 |
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| Synonyms: | CHEMBL3289393 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H18N5O11P3S |
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| Mol. Mass. | 521.274 |
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| SMILES | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@@](O)(=S)OP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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