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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neurotensin receptor type 2 | ||
| Ligand | BDBM50019413 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1364514 (CHEMBL3295311) | ||
| EC50 | 20±n/a nM | ||
| Citation |  Thomas, JB; Giddings, AM; Wiethe, RW; Olepu, S; Warner, KR; Sarret, P; Gendron, L; Longpre, JM; Zhang, Y; Runyon, SP; Gilmour, BP Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound. J Med Chem57:5318-32 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neurotensin receptor type 2 | |||
| Name: | Neurotensin receptor type 2 | ||
| Synonyms: | High-affinity levocabastine-sensitive neurotensin receptor | NT-R-2 | NTR2_RAT | Neurotensin receptor 2 | Neurotensin receptor type 2 | Ntr2 | Ntsr2 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 46280.50 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_1466615 | ||
| Residue: | 416 | ||
| Sequence: |
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| BDBM50019413 | |||
| n/a | |||
| Name | BDBM50019413 | ||
| Synonyms: | CHEMBL3290097 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H25ClN4O5 | ||
| Mol. Mass. | 520.964 | ||
| SMILES | COc1cccc(OC)c1-c1cc(nn1-c1ccnc2cc(Cl)ccc12)C(=O)NC1(CCCC1)C(O)=O |(21.16,-18.01,;21.64,-16.55,;23.14,-16.23,;24.17,-17.37,;25.68,-17.05,;26.15,-15.59,;25.12,-14.44,;25.6,-12.98,;27.11,-12.66,;23.62,-14.76,;22.28,-13.28,;22.6,-11.77,;21.26,-11,;20.12,-12.03,;20.75,-13.44,;19.75,-15.17,;20.52,-16.5,;19.75,-17.84,;18.21,-17.84,;17.44,-16.5,;15.9,-16.5,;15.13,-15.17,;13.59,-15.17,;15.9,-13.84,;17.44,-13.84,;18.21,-15.17,;21.1,-9.47,;22.35,-8.56,;19.7,-8.84,;19.54,-7.31,;21.08,-7.31,;21.55,-5.85,;20.31,-4.94,;19.06,-5.85,;18.03,-7.63,;17,-6.49,;17.55,-9.09,)| | ||
| Structure | 
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