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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neurotensin receptor type 2 | ||
| Ligand | BDBM50019411 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1364517 (CHEMBL3295314) | ||
| Ki | 170±n/a nM | ||
| Citation |  Thomas, JB; Giddings, AM; Wiethe, RW; Olepu, S; Warner, KR; Sarret, P; Gendron, L; Longpre, JM; Zhang, Y; Runyon, SP; Gilmour, BP Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound. J Med Chem57:5318-32 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neurotensin receptor type 2 | |||
| Name: | Neurotensin receptor type 2 | ||
| Synonyms: | High-affinity levocabastine-sensitive neurotensin receptor | NT-R-2 | NTR2_RAT | Neurotensin receptor 2 | Neurotensin receptor type 2 | Ntr2 | Ntsr2 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 46280.50 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_1466615 | ||
| Residue: | 416 | ||
| Sequence: |
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| BDBM50019411 | |||
| n/a | |||
| Name | BDBM50019411 | ||
| Synonyms: | CHEMBL3290095 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H29ClN4O5 | ||
| Mol. Mass. | 549.017 | ||
| SMILES | COc1cccc(OC)c1-c1cc(nn1-c1ccnc2cc(Cl)ccc12)C(=O)NC1(CCCCCC1)C(O)=O |(20.7,-18.03,;21.17,-16.57,;22.68,-16.25,;23.71,-17.39,;25.22,-17.07,;25.69,-15.61,;24.66,-14.46,;25.14,-13,;26.64,-12.68,;23.16,-14.78,;21.82,-13.29,;22.14,-11.79,;20.8,-11.02,;19.66,-12.05,;20.28,-13.46,;19.28,-15.19,;20.05,-16.52,;19.28,-17.86,;17.74,-17.86,;16.97,-16.52,;15.43,-16.52,;14.66,-15.19,;13.12,-15.19,;15.43,-13.86,;16.97,-13.86,;17.74,-15.19,;20.64,-9.49,;21.89,-8.58,;19.23,-8.86,;19.05,-7.34,;20.61,-7.52,;21.7,-6.43,;21.54,-4.9,;20.24,-4.07,;18.78,-4.57,;18.28,-6.01,;17.62,-7.83,;16.42,-6.86,;17.32,-9.34,)| | ||
| Structure | 
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