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TargetGPR103
LigandBDBM50019983
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1363386
IC50 79±n/a nM
Citation Nordqvist AKristensson LJohansson KEIsaksson da Silva KFex TTyrchan CSvensson Henriksson ANilsson K New Hits as Antagonists of GPR103 Identified by HTS. ACS Med Chem Lett 5:527-32 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
GPR103
Name:GPR103
Synonyms:Pyroglutamylated RFamide peptide receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:49508.46
Organism:Homo sapiens (Human)
Description:GPR103 0 HUMAN::Q96P65
Residue:431
Sequence:
MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALAL
FGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKM
VPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPM
WHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYE
LWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSN
FEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQ
RHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSE
LAENSPLDSGH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50019983
n/a
NameBDBM50019983
Synonyms:CHEMBL3287585
TypeSmall organic molecule
Emp. Form.C20H25ClN2O4S
Mol. Mass.424.941
SMILESCOc1ccc(Cl)cc1NS(=O)(=O)c1ccc(OC)c2C[C@@H](CCc12)N(C)C |r|
Structure
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