Reaction Details |
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Target | Accessory gene regulator protein A |
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Ligand | BDBM50020375 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1366621 (CHEMBL3296715) |
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IC50 | 12±n/a nM |
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Citation | Figueroa, M; Jarmusch, AK; Raja, HA; El-Elimat, T; Kavanaugh, JS; Horswill, AR; Cooks, RG; Cech, NB; Oberlies, NH Polyhydroxyanthraquinones as quorum sensing inhibitors from the guttates of Penicillium restrictum and their analysis by desorption electrospray ionization mass spectrometry. J Nat Prod77:1351-8 (2014) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Accessory gene regulator protein A |
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Name: | Accessory gene regulator protein A |
Synonyms: | AGRA_STAAU | agr | agrA |
Type: | PROTEIN |
Mol. Mass.: | 27903.57 |
Organism: | Staphylococcus aureus |
Description: | ChEMBL_1366621 |
Residue: | 238 |
Sequence: | MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDI
QLSTDINGIKLGSEIRKHDPVGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRI
IDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIMFFESSTKSHRLIAHLDNRQI
EFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI
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BDBM50020375 |
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n/a |
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Name | BDBM50020375 |
Synonyms: | CHEMBL3289785 |
Type | Small organic molecule |
Emp. Form. | C38H58N10O12S |
Mol. Mass. | 878.992 |
SMILES | CC(C)C[C@@H]1NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CSC(=O)[C@H](Cc2ccccc2)NC1=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)CN)C(C)C |r| |
Structure |
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