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TargetHuman immunodeficiency virus type 1 integrase
LigandBDBM50021284
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1366289
Kd 59±n/a nM
Citation Fader LDCarson RMorin SBilodeau FChabot CHalmos TBailey MDKawai SHCoulombe RLaplante SMekhssian KJakalian AGarneau MDuan JMason SWSimoneau BFenwick CTsantrizos YYoakim C Minimizing the Contribution of Enterohepatic Recirculation to Clearance in Rat for the NCINI Class of Inhibitors of HIV. ACS Med Chem Lett 5:711-6 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 integrase
Name:Human immunodeficiency virus type 1 integrase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:32231.48
Organism:Human immunodeficiency virus 1
Description:ChEMBL_90865
Residue:288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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  Blast E-value cutoff:
BDBM50021284
n/a
NameBDBM50021284
Synonyms:CHEMBL3287917
TypeSmall organic molecule
Emp. Form.C32H35N3O4
Mol. Mass.525.638
SMILESCc1nc(c(C)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O)-c1cccc(c1)-c1cnn(C)c1 |r|
Structure
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