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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Muscarinic acetylcholine receptor M1 | ||
| Ligand | BDBM50021905 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1367094 | ||
| Ki | 0.190000±n/a nM | ||
| Citation |  Nagashima, S; Matsushima, Y; Hamaguchi, H; Nagata, H; Kontani, T; Moritomo, A; Koshika, T; Takeuchi, M Novel quinuclidinyl heteroarylcarbamate derivatives as muscarinic receptor antagonists. Bioorg Med Chem22:3478-87 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Muscarinic acetylcholine receptor M1 | |||
| Name: | Muscarinic acetylcholine receptor M1 | ||
| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 51390.46 | ||
| Organism: | RAT | ||
| Description: | P08482 | ||
| Residue: | 460 | ||
| Sequence: |
| ||
| BDBM50021905 | |||
| n/a | |||
| Name | BDBM50021905 | ||
| Synonyms: | CHEMBL3298589 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H21ClN2O2S | ||
| Mol. Mass. | 364.89 | ||
| SMILES | Cl.O=C(Nc1ccsc1-c1ccccc1)O[C@H]1CN2CCC1CC2 |r,wD:16.16,(41.69,-11.32,;44.26,-6.71,;42.92,-7.48,;41.59,-6.7,;41.6,-5.16,;42.84,-4.27,;42.37,-2.81,;40.83,-2.8,;40.35,-4.27,;38.89,-4.74,;37.74,-3.7,;36.28,-4.18,;35.96,-5.69,;37.11,-6.72,;38.57,-6.24,;42.92,-9.02,;44.25,-9.79,;44.25,-11.32,;45.58,-12.1,;46.92,-11.33,;46.92,-9.78,;45.61,-9.01,;44.85,-10.35,;46.34,-10.75,)| | ||
| Structure | 
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