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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50023218
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1368488 (CHEMBL3300408)
Ki 0.950000±n/a nM
Citation Laurini, EHarel, DMarson, DSchepmann, DSchmidt, TJPricl, SWünsch, B Identification, pharmacological evaluation and binding mode analysis of novel chromene and chromane baseds1 receptor ligands. Eur J Med Chem83:526-33 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:Protein
Mol. Mass.:25307.17
Organism:Cavia porcellus (Guinea pig)
Description:Q60492
Residue:223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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BDBM50023218
n/a
NameBDBM50023218
Synonyms:CHEMBL2435438
TypeSmall organic molecule
Emp. Form.C24H31NO2
Mol. Mass.365.5084
SMILESCOc1cc2OC(C)(C)C=Cc2cc1C(C)N(C)CCCc1ccccc1 |c:9|
Structure
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