| Reaction Details |
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 | Report a problem with these data |
| Target | Env polyprotein |
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| Ligand | BDBM50023612 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1455137 (CHEMBL3366750) |
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| EC50 | 20±n/a nM |
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| Citation |  Wang, C; Lu, L; Na, H; Li, X; Wang, Q; Jiang, X; Xu, X; Yu, F; Zhang, T; Li, J; Zhang, Z; Zheng, B; Liang, G; Cai, L; Jiang, S; Liu, K Conjugation of a nonspecific antiviral sapogenin with a specific HIV fusion inhibitor: a promising strategy for discovering new antiviral therapeutics. J Med Chem57:7342-54 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Env polyprotein |
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| Name: | Env polyprotein |
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| Synonyms: | ENV | GP41 | HIV1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 14017.92 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_109731 |
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| Residue: | 124 |
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| Sequence: | FLGFLGAAGSTMGAASITLTVQARTLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQA
RVLAVERYLQDQQLLGIWGCSGKHICTTTVPWNSSWSNKSLEEIWQNMTWMEWEREIDNY
TGLI
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| BDBM50023612 |
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| n/a |
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| Name | BDBM50023612 |
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| Synonyms: | CHEMBL3341852 |
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| Type | Small organic molecule |
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| Emp. Form. | C177H280N44O56 |
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| Mol. Mass. | 3920.3783 |
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| SMILES | [H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)OCc1cn(CC(=O)NCCCC[C@H](NC(=O)CCNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(C)=O)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)C(N)=O)nn1)C(C)=C |r| |
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| Structure | 
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