Reaction Details |
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Target | Cytosol aminopeptidase [33-68,L62W] |
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Ligand | BDBM50024597 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1442056 (CHEMBL3373424) |
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Ki | 220±n/a nM |
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Citation | Vassiliou, S; Weglarz-Tomczak, E; Berlicki, L; Pawelczak, M; Nocek, B; Mulligan, R; Joachimiak, A; Mucha, A Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J Med Chem57:8140-51 (2014) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Cytosol aminopeptidase [33-68,L62W] |
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Name: | Cytosol aminopeptidase [33-68,L62W] |
Synonyms: | AMPL_PIG | Cytosol aminopeptidase | LAP3 | Leucine aminopeptidase (LAP) |
Type: | Enzyme |
Mol. Mass.: | 4015.44 |
Organism: | Sus scrofa (Pig) |
Description: | P28839[33-68,L62W] |
Residue: | 36 |
Sequence: | TKGLVLGIYSKEKEDDAPQFTSAGENFDKWVSGKLR
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BDBM50024597 |
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n/a |
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Name | BDBM50024597 |
Synonyms: | (S)-1-Ammonium-3-methyl-butane-1-phosphonic acid anion | CHEMBL288165 |
Type | Small organic molecule |
Emp. Form. | C5H14NO3P |
Mol. Mass. | 167.1433 |
SMILES | CC(C)C[C@@H]([NH3+])P(O)([O-])=O |
Structure |
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