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TargetLeucine aminopeptidase (LAP)
LigandBDBM50025046
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1442056
Ki 215±n/a nM
Citation Vassiliou SWeglarz-Tomczak EBerlicki LPawelczak MNocek BMulligan RJoachimiak AMucha A Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J Med Chem 57:8140-51 (2014) [PubMed]  Article
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Leucine aminopeptidase (LAP)
Name:Leucine aminopeptidase (LAP)
Synonyms:Cytosol aminopeptidase
Type:Enzyme
Mol. Mass.:4015.44
Organism:Sus scrofa (Pig)
Description:P28839
Residue:36
Sequence:
TKGLVLGIYSKEKEDDAPQFTSAGENFDKWVSGKLR
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BDBM50025046
n/a
NameBDBM50025046
Synonyms:CHEMBL3355101
TypeSmall organic molecule
Emp. Form.C19H23N2O6P
Mol. Mass.406.3695
SMILESNC(CCc1ccc(cc1)[N+]([O-])=O)P(O)(=O)CC(Cc1ccccc1)C(O)=O
Structure
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