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TargetLeucine aminopeptidase (LAP)
LigandBDBM50025070
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1442056
Ki 74±n/a nM
Citation Vassiliou SWeglarz-Tomczak EBerlicki LPawelczak MNocek BMulligan RJoachimiak AMucha A Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J Med Chem 57:8140-51 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Leucine aminopeptidase (LAP)
Name:Leucine aminopeptidase (LAP)
Synonyms:Cytosol aminopeptidase
Type:Enzyme
Mol. Mass.:4015.44
Organism:Sus scrofa (Pig)
Description:P28839
Residue:36
Sequence:
TKGLVLGIYSKEKEDDAPQFTSAGENFDKWVSGKLR
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  Blast E-value cutoff:
BDBM50025070
n/a
NameBDBM50025070
Synonyms:CHEMBL3355110
TypeSmall organic molecule
Emp. Form.C19H26N3O4P
Mol. Mass.391.4012
SMILESNCc1ccc(CC(CP(O)(=O)C(N)CCc2cccnc2)C(O)=O)cc1
Structure
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