| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50026748 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1437451 (CHEMBL3387261) |
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| IC50 | 0.052000±n/a nM |
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| Citation |  Wang, X; Liu, L; Huang, L; Herbst-Robinson, K; Cornec, AS; James, MJ; Sugiyama, S; Bassetto, M; Brancale, A; Trojanowski, JQ; Lee, VM; Smith, AB; Brunden, KR; Ballatore, C Potent, long-acting cyclopentane-1,3-Dione thromboxane (A2)-receptor antagonists. ACS Med Chem Lett5:1015-20 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
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| Type: | Enyzme |
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| Mol. Mass.: | 37445.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21731 |
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| Residue: | 343 |
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| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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| BDBM50026748 |
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| n/a |
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| Name | BDBM50026748 |
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| Synonyms: | CHEMBL3354616 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H28ClNO5S |
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| Mol. Mass. | 538.054 |
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| SMILES | COc1ccc(cc1)C1=C(O)CC(Cc2cccc3CC(CCc23)NS(=O)(=O)c2ccc(Cl)cc2)C1=O |c:9| |
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| Structure | 
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