| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50026819 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1438219 (CHEMBL3390251) |
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| Ki | 3280±n/a nM |
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| Citation |  Moss, SM; Jayasekara, PS; Paoletta, S; Gao, ZG; Jacobson, KA Structure-Based Design of Reactive Nucleosides for Site-Specific Modification of the A2A Adenosine Receptor. ACS Med Chem Lett5:1043-8 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50026819 |
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| n/a |
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| Name | BDBM50026819 |
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| Synonyms: | CHEMBL3335525 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H47N11O10S |
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| Mol. Mass. | 861.923 |
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| SMILES | [H][C@]12CS[C@@H](CCCCC(=O)Oc3ccc(NC(=O)CCc4ccc(CCNc5nc(N)c6ncn([C@@H]7O[C@@H]([C@@H](O)[C@H]7O)C(=O)NCC)c6n5)cc4)cc3[N+]([O-])=O)[C@@]1([H])NC(=O)N2 |r| |
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| Structure | 
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