| Reaction Details |
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 | Report a problem with these data |
| Target | C5a anaphylatoxin chemotactic receptor 1 |
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| Ligand | BDBM150811 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1436210 (CHEMBL3386572) |
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| IC50 | >5000±n/a nM |
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| Citation |  Maeda, DY; Peck, AM; Schuler, AD; Quinn, MT; Kirpotina, LN; Wicomb, WN; Fan, GH; Zebala, JA Discovery of 2-[5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanylmethyl]phenylboronic Acid (SX-517): Noncompetitive Boronic Acid Antagonist of CXCR1 and CXCR2. J Med Chem57:8378-97 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C5a anaphylatoxin chemotactic receptor 1 |
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| Name: | C5a anaphylatoxin chemotactic receptor 1 |
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| Synonyms: | C5AR | C5AR1 | C5AR1_HUMAN | C5R1 | C5a anaphylatoxin chemotactic receptor | C5a anaphylatoxin chemotactic receptor (C5aR) | C5a-R | CD_antigen=CD88 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39347.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21730 |
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| Residue: | 350 |
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| Sequence: | MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVW
VTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNM
YASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREE
YFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKT
LKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIY
VVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
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| BDBM150811 |
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| n/a |
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| Name | BDBM150811 |
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| Synonyms: | US8981106, 1 (SX-517) | USRE47267, Compound 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16BFN2O3S |
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| Mol. Mass. | 382.216 |
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| SMILES | OB(O)c1ccccc1CSc1ccc(cn1)C(=O)Nc1ccc(F)cc1 |
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| Structure | 
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