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Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 1 | ||
| Ligand | BDBM50029928 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1438383 (CHEMBL3383058) | ||
| Ki | 1011±n/a nM | ||
| Citation |  Lucchesi, V; Hurst, DP; Shore, DM; Bertini, S; Ehrmann, BM; Allarà, M; Lawrence, L; Ligresti, A; Minutolo, F; Saccomanni, G; Sharir, H; Macchia, M; Di Marzo, V; Abood, ME; Reggio, PH; Manera, C CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides. J Med Chem57:8777-91 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 1 | |||
| Name: | Cannabinoid receptor 1 | ||
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 52868.96 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21554 | ||
| Residue: | 472 | ||
| Sequence: |
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| BDBM50029928 | |||
| n/a | |||
| Name | BDBM50029928 | ||
| Synonyms: | CHEMBL3353436 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H26FN3O2 | ||
| Mol. Mass. | 359.4377 | ||
| SMILES | CC1CCC(CC1)NC(=O)c1cc2cccnc2n(CCCCF)c1=O |(13.03,.29,;11.7,-.5,;11.7,-2.04,;10.37,-2.81,;9.03,-2.04,;9.02,-.51,;10.36,.28,;7.7,-2.82,;6.36,-2.06,;6.36,-.52,;5.04,-2.83,;3.7,-2.07,;2.37,-2.85,;1.04,-2.08,;-.3,-2.85,;-.3,-4.4,;1.04,-5.17,;2.38,-4.39,;3.71,-5.16,;3.71,-6.7,;5.05,-7.46,;5.05,-9,;6.39,-9.77,;6.39,-11.31,;5.04,-4.38,;6.38,-5.15,)| | ||
| Structure | 
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