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Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 1 | ||
| Ligand | BDBM50029968 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1438383 (CHEMBL3383058) | ||
| Ki | >10000±n/a nM | ||
| Citation |  Lucchesi, V; Hurst, DP; Shore, DM; Bertini, S; Ehrmann, BM; Allarà, M; Lawrence, L; Ligresti, A; Minutolo, F; Saccomanni, G; Sharir, H; Macchia, M; Di Marzo, V; Abood, ME; Reggio, PH; Manera, C CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides. J Med Chem57:8777-91 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 1 | |||
| Name: | Cannabinoid receptor 1 | ||
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 52868.96 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21554 | ||
| Residue: | 472 | ||
| Sequence: |
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| BDBM50029968 | |||
| n/a | |||
| Name | BDBM50029968 | ||
| Synonyms: | CHEMBL3353425 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H23N3O3 | ||
| Mol. Mass. | 329.3935 | ||
| SMILES | CC1CCC(CC1)NC(=O)c1cc2cccnc2n(CCO)c1=O |(40.53,3.04,;39.2,2.26,;39.2,.72,;37.88,-.05,;36.54,.72,;36.53,2.25,;37.87,3.03,;35.22,-.06,;33.88,.71,;33.87,2.25,;32.56,-.07,;31.22,.7,;29.9,-.09,;28.57,.69,;27.24,-.09,;27.24,-1.63,;28.57,-2.4,;29.9,-1.63,;31.23,-2.39,;31.24,-3.93,;29.91,-4.7,;29.91,-6.24,;32.56,-1.62,;33.9,-2.38,)| | ||
| Structure | 
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